Souder's investigates how social workers determine when their services are no longer effective. In this view, the social worker has an ethical obligation to serve the client, and clear evaluative methods must be in place that takes into account the ethics of treatment for the client (Souders, 2009)
This can cause a serious hardship in the relationships of the person with BPD, especially upon family, children, and co-workers. Using conflict resolution strategies can enable those with BPD to have an acceptable and appropriate framework for approaching relationships in a positive manner (Sperry, 2003)
MRI imaging of people with BPD show a marked decrease in prefrontal regulation of amygdala-generated neural responses (Ruocco, Medaglia, Ayaz, & Chute, 2010). Additionally, people with BPD have decreased activity in certain brain neurotransmitters, such as serotonin, dopamine, acetylcholine, and norepinephrin, likely due to genetic factors that are aggravated in stress situations (Steele & Siever, 2010)
Drugs that act to enhance and sustain levels of these neurotransmitters in the neuron's pre-synaptic gap for longer periods tend to reduce symptoms of Borderline Personality Disorder. Drugs that stabilize the inhibitory neurotransmitter GABA are shown to help stabilize the mood of those with BPD as well, reducing the ideation-mood disturbance episodes common in BPD (Stoffers, Vollm, Rucker, Timmer, Huband, & Lieb, 2010)
Additionally, people with BPD may have predisposing factors, such as genetics, brain and neurobiological issues, and other environmental variables. Moreover, BPD may result from an inability to effectively deal with adolescent stress events (Zanarini & Frankenburg, 1997)