These researchers add that, "hnRNP A2/B1 protein is a major component of the hnRNP core complex in mammalian cell nuclei. Although the function of hnRNP A2/B1 has not yet been fully elucidated, recent studies have revealed that hnRNP A2/B1 is involved in RNA splicing in nuclei as well as in mRNA transport from nucleus to cytoplasm" (Sueoka et al
These researchers add that, "hnRNP A2/B1 protein is a major component of the hnRNP core complex in mammalian cell nuclei. Although the function of hnRNP A2/B1 has not yet been fully elucidated, recent studies have revealed that hnRNP A2/B1 is involved in RNA splicing in nuclei as well as in mRNA transport from nucleus to cytoplasm" (Sueoka et al
These researchers add that, "hnRNP A2/B1 protein is a major component of the hnRNP core complex in mammalian cell nuclei. Although the function of hnRNP A2/B1 has not yet been fully elucidated, recent studies have revealed that hnRNP A2/B1 is involved in RNA splicing in nuclei as well as in mRNA transport from nucleus to cytoplasm" (Sueoka et al
These researchers are quick to point out, though, that, "hnRNPs can hinder communication between factors bound to different splice-sites, thereby having a positive role in RNA splicing. Most importantly, the concentration of splicing factors can alter the kinetic equilibrium in splicing, resulting in changes in splice-site selection" (Torosyan et al