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Systemic Lupus Case Study


Laboratory tests will probably reveal the following: 1. ANA titer above 1:40 (Gill, Quisell, Rocca, and Walters, 2003) 2

Systemic Lupus Case Study


Madhok and Wu (2009) examined the research literature for studies investigating the efficacy of medications commonly used to treat SLE and found the number of high-quality randomized controlled trials was limited. Drug efficacy for treating SLE symptoms continues to be a central focus of lupus research, although there is growing interest in biological (Hedberg, Kanapathippillai, Rekviq, and Fenton, 2013) and alternative medical treatments (Zhong et al

Systemic Lupus Case Study


Systemic Lupus Erythematosus Case Study Systemic Lupus Erythematosus Systemic lupus erythematosus (SLE) is a chronic, life-long autoimmune disease that affects multiple tissues and organs in the body (Madhok and Wu, 2009)

Systemic Lupus Case Study


ANA titer above 1:40 (Gill, Quisell, Rocca, and Walters, 2003) 2. CBC revealing lower than normal RBC count, hemoglobin, and hematocrit indicating iron deficiency (Schrier, 2013) or a positive erythrocyte antibody screen consistent with a diagnosis of hemolytic anemia (ABSCM) (Mayo Medical Laboratories, 2013) 3

Systemic Lupus Case Study


Madhok and Wu (2009) examined the research literature for studies investigating the efficacy of medications commonly used to treat SLE and found the number of high-quality randomized controlled trials was limited. Drug efficacy for treating SLE symptoms continues to be a central focus of lupus research, although there is growing interest in biological (Hedberg, Kanapathippillai, Rekviq, and Fenton, 2013) and alternative medical treatments (Zhong et al

Lupus - Systemic Lupus Erythematosus


The intended consequence would be for the body to fight infection and for the person to live normally (Podiatry Now). CellCept drug for the treatment of kidney complications could be a boon to lupus patients (Chang, 2005)

Lupus - Systemic Lupus Erythematosus


Joseph McCune of the University of Michigan Medical Center commented that it would be reasonable for doctors to prescribe the drug to patients who were concerned about fertility (Chang). Prognosis Short and midterm survival among SLE patients was said to have significantly improved in the last three decades (Jancin, 2006)

Lupus - Systemic Lupus Erythematosus


If all of them were identical, the race should have perished (NWHRC). Complications SLE increases a woman's risk for cardiovascular disease more than two times (Kubetin, 2008)

Lupus - Systemic Lupus Erythematosus


Those who developed SLE mostly developed hypertension, diabetes and cardiovascular disease (Kubetin). Diagnosis Doctors recommend early detection to reduce the chance of organ damage and other complications (Meadows, 2005)

Lupus - Systemic Lupus Erythematosus


These fetuses also often develop a congenital heart block (NWHRC). Drug-induced lupus develops from the use of minocycline intended for acne and hydralazine intended for heart failure (Walsh, 2008)

Oral Lupus: Etiology, Epidemiology, and Clinical Decisions


Once a diagnosis of LE has been confirmed the next objective is to treat the oral lesions using appropriate medications and care plan. Oral lesions in patients undergoing systemic treatment for LE will often resolve without additional interventions; however, topical treatments are often prescribed for patients (Brennan, Valerin, Napenas, & Lockhart, 2005)

Oral Lupus: Etiology, Epidemiology, and Clinical Decisions


In the absence of a diagnosis and effective treatment, the risk of serious complications and even death is significant. BRIEF 2: The oral manifestations of SLE include discoid lesions, honeycomb plaques, raised keratotic plaques (horny growth similar to warts), erythema (capillary dilation), purpura (small hemorrhage), petechiae (sub-epidermal hemorrhage), cheilitis (inflammation and cracking of lips), and ulcers with an irregular shape (Chi, Neville, Krayer, & Gonsalves, 2010)

Oral Lupus: Etiology, Epidemiology, and Clinical Decisions


Lesions will develop in patients suffering from CLE, but only in the presence of skin lesions. Researchers examined the oral lesions of 46 patients with a confirmed diagnosis of SLE or CLE and found the most common oral lesion to be lichenoid mucositis (Lourenco et al

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